RET-IN-29

CAT: 0931-MF-0114024-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0114024-01Size:10 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
C-RET
Related Pathways
Tyrosine Kinase/Adaptors|||Apoptosis
Bioactivity
RET-IN-29 (Compound 8W) is a selective RET kinase inhibitor. It demonstrates inhibitory effects on BaF3 cells with the CCDC6-RETV804M mutation, with an IC50 of 0.715 ?M. RET-IN-29 shows potential for research in non-small cell lung cancer (NSCLC) .
Smiles
O=C(C=C1C)N(C2CCC2)C3=C1C=NC(NC4=NN(C5=C(C)C=CC=C5)C=C4)=N3
Molecular Formula
C22H22N6O
Molecular Weight
386.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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