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RET-IN-29

CAT: 0013-GTR19249099-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249099-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RET-IN-29 (Compound 8W) is a selective RET kinase inhibitor with an IC50 of 0.715 μM against BaF3 cells harboring the CCDC6-RETV804M mutation. This compound is a useful research tool for investigating RET-driven oncogenesis, particularly in non-small cell lung cancer (NSCLC) models, both in vitro and in vivo.
Field of Research
Cell Biology, Signal Transduction
Smiles
O=C (C=C1C) N (C2CCC2) C3=C1C=NC (NC4=NN (C5=C (C) C=CC=C5) C=C4) =N3
Molecular Formula
C22H22N6O
Molecular Weight
386.45
Storage Conditions
-20°C
Notes
For research use only.

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