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Antidepressant agent 9

CAT: 0931-T205640-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205640-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
143899-90-5
Target
Serotonin Transporter, iGluR
Related Pathways
Membrane transporter/Ion channel, Neuroscience
Bioactivity
Antidepressant agent 9 (Compound 24) is an orally active inhibitor of NMDAR and SERT, with IC50 values of 3.50 μM and 1044 nM, respectively. It exhibits good metabolic stability and plasma exposure, and demonstrates antidepressant-like effects in the forced swim test in mice.
Smiles
CN1[C@@]2([C@@]3([C@@](C=4C(C2)=CC=C(N)C4)(CC1)CCCC3)[H])[H]
Molecular Formula
C17H24N2
Molecular Weight
256.386
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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