Antidepressant agent 9

• CAS Number :

  143899-90-5

• Target :

  Serotonin Transporter|||iGluR

• Related Pathways :

  Membrane transporter/Ion channel|||Neuroscience

• Bioactivity :

  Antidepressant agent 9 (Compound 24) is an orally active inhibitor of NMDAR and SERT, with IC50 values of 3.50 ?M and 1044 nM, respectively. It exhibits good metabolic stability and plasma exposure, and demonstrates antidepressant-like effects in the forced swim test in mice.

• Smiles :

  CN1[C@@]2([C@@]3([C@@](C=4C(C2)=CC=C(N)C4)(CC1)CCCC3)[H])[H]

• Molecular Formula :

  C17H24N2

• Molecular Weight :

  256.386

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C