DDO-8958

• CAS Number :

  3017180-18-3

• Target :

  Epigenetic Reader Domain|||Apoptosis

• Related Pathways :

  Apoptosis|||Chromatin/Epigenetic

• Bioactivity :

  DDO-8958 is an orally active and selective BET BD1 inhibitor, exhibiting a KD of 5.6 nM for BRD4 BD1. It shows low nanomolar inhibitory activity across all BET BD1 bromodomains except for BRDT BD1. DDO-8958 inhibits tumor cell proliferation and migration, induces apoptosis and cell cycle arrest, and demonstrates antitumor activity.

• Smiles :

  FC=1C(=CC(OCC2COC2)=CC1C=3C(=NN(C3C)C)C)C4=CC=NC=5N=CNC54

• Molecular Formula :

  C22H22FN5O2

• Molecular Weight :

  407.441

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C