DDO-4033

CAT: 0931-T212005-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T212005-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

E1/E2/E3 Enzyme, YAP

Related Pathways

Stem Cells, Ubiquitination

Bioactivity

DDO-4033 is an SPOP inhibitor with an IC50 of 16.9 μM and a Kd of 15.1 μM. It hinders the malignant migration, invasion, and proliferation of clear cell renal cell carcinoma (ccRCC) cell lines. DDO-4033 disrupts the recruitment of the substrate LATS1 by SPOP, inhibiting its polyubiquitination and subsequent degradation, which leads to the upregulation of LATS1 expression. This compound demonstrates significant antitumor activity and can be utilized in renal cell carcinoma research.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
HY-175247	DDO-4033
TRC-L397620-25MG	LGD-4033
453724-01	LGD-4033 discontinued
A14346-200	Ligandrol (LGD-4033) 200mg
A14346-10	Ligandrol (LGD-4033) 10mg
A14346-100	Ligandrol (LGD-4033) 100mg
A14346-5	Ligandrol (LGD-4033) 5mg
CSB-CL006593HU	DDO
163355	Anti LGD 4033 Pab
A14346-50	Ligandrol (LGD-4033) 50mg

DDO-4033

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