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P162-0948

CAT: 0931-T205592-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T205592-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1358201-44-1
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
P162-0948 is a selective CDK8 inhibitor with an IC50 value of 50.4 nM. It reduces cell migration and the expression of EMT-related proteins in the A549 human alveolar epithelial cell line. Furthermore, P162-0948 decreases Smad phosphorylation, indicating disruption of the TGF-?/Smad signaling pathway, making it a promising compound for pulmonary fibrosis research.
Smiles
O=C(NCC1=CC=C(F)C=C1)CC2=NN=C(O2)C=3C=CC=4N=CC=CC4C3
Molecular Formula
C20H15FN4O2
Molecular Weight
362.357
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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Alternative Products

CatalogName
HY-170813P162-0948
362922EEA1 (Early Endosome Antigen 1, ZFYVE2, Endosome-associated protein p162, Zinc finger FYVE domain-containing protein 2)
222309-01EEA1 (Early endosome Antigen 1, Endosome-Associated Protein p162, Zinc Finger FYVE Domain-Containing Protein 2, ZFYVE2) discontinued
126164-PEEEA1 (ZFYVE2, Early Endosome Antigen 1, Endosome-associated Protein p162, Zinc Finger FYVE Domain-containing Protein 2, MSTP105, MST105) (PE) discontinued
126164EEA1 (ZFYVE2, Early Endosome Antigen 1, Endosome-associated Protein p162, Zinc Finger FYVE Domain-containing Protein 2, MSTP105, MST105) discontinued
E2211-02EEA1 (Early Endosomal Antigen 1, Early Endosome Associated Protein, Endosome Associated Protein p162, ZFYVE2, Zinc Finger FYVE Domain Containing Protein 2) discontinued
126164-HRPEEA1 (ZFYVE2, Early Endosome Antigen 1, Endosome-associated Protein p162, Zinc Finger FYVE Domain-containing Protein 2, MSTP105, MST105) (HRP) discontinued
MBS600540-01EEA1 (Early Endosomal Antigen 1, Early Endosome Associated Protein, Endosome Associated Protein p162, ZFYVE2, Zinc Finger FYVE Domain Containing Protein 2)
126164-BiotinEEA1 (ZFYVE2, Early Endosome Antigen 1, Endosome-associated Protein p162, Zinc Finger FYVE Domain-containing Protein 2, MSTP105, MST105) (Biotin) discontinued
126164-APEEA1 (ZFYVE2, Early Endosome Antigen 1, Endosome-associated Protein p162, Zinc Finger FYVE Domain-containing Protein 2, MSTP105, MST105) (AP) discontinued

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