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AChE-IN-82

CAT: 0931-T205513-01Size: 10 mgDry Ice: NoHazardous: No
CAT#: T205513-01Size: 10 mg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Cholinesterase (ChE) |||Beta-Secretase|||COX|||Lipoxygenase|||Monoamine Oxidase
Related Pathways
Metabolism|||Immunology/Inflammation|||Neuroscience
Bioactivity
AChE-IN-82 (compound 49) is an acetylcholinesterase (AChE) inhibitor. It inhibits eeAChE, eqBChE, hMAO-A, hMAO-B, and BACE-1 with IC50 values of 0.072, 9.81, 14.52, 0.024, and 2.42 ?M, respectively. Additionally, AChE-IN-82 inhibits COX-1, COX-2, and 5-LOX with IC50 values of 60.41, 0.187, and 0.18 ?M, respectively. The compound also demonstrates strong neuroprotective effects by significantly reducing H2O2-induced oxidative stress.
Molecular Formula
C21H18N4O5S2
Molecular Weight
470.52
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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Alternative Products

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HY-170938AChE-IN-82
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