P38-? MAPK-IN-9

• Target:

  P38 MAPK

• Related Pathways:

  MAPK

• Bioactivity:

  P38-? MAPK-IN-9 (Compound 25a) is a p38-? MAPK inhibitor with a Ki value of 0.057 nM. It effectively inhibits LPS-induced TNF? production in hPBMC cells, exhibiting an IC50 of 18 nM.

• Smiles:

  N#CC=1C (=NC (=NC1NC (C) C) N) NC2=CC (=CC=C2C) C (=O) NC3=NOC=C3

• Molecular Formula:

  C19H20N8O2

• Molecular Weight:

  392.414

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  868272-50-8