P38-α MAPK-IN-9

CAT: 0931-T205389-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T205389-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

868272-50-8

Target

P38 MAPK

Related Pathways

MAPK

Bioactivity

P38-α MAPK-IN-9 (Compound 25a) is a p38-α MAPK inhibitor with a Ki value of 0.057 nM. It effectively inhibits LPS-induced TNFα production in hPBMC cells, exhibiting an IC50 of 18 nM.

Smiles

N#CC=1C(=NC(=NC1NC(C)C)N)NC2=CC(=CC=C2C)C(=O)NC3=NOC=C3

Molecular Formula

C19H20N8O2

Molecular Weight

392.414

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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HY-171254	P38-α MAPK-IN-9
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P38-α MAPK-IN-9

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