STAT5-IN-3

CAT: 0931-T205367-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T205367-01Size:10 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
STAT
Related Pathways
Stem Cells|||JAK/STAT signaling
Bioactivity
STAT5-IN-3 (Compound 14a) is a STAT5 inhibitor with anticancer properties. It works by blocking the tyrosine phosphorylation of STAT5A/5B at the Y694/699 sites, significantly reducing the expression of the STAT5B protein. This leads to the inhibition of downstream gene transcription, thereby preventing the proliferation and survival of leukemia cells. Additionally, STAT5-IN-3 has significant potential in overcoming chemotherapy resistance.
Molecular Formula
C25H27N5O
Molecular Weight
413.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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