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STAT1/3-IN-1

CAT: 0931-T204879-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204879-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2958649-56-2
Target
COX, STAT, Interleukin, NO Synthase
Related Pathways
Neuroscience, JAK/STAT signaling, Stem Cells, Immunology/Inflammation
Bioactivity
STAT1/3-IN-1 (Compound 6k) is an inhibitor of STAT1/3 phosphorylation. It prevents the phosphorylation and nuclear translocation of STAT1/3. Additionally, STAT1/3-IN-1 inhibits the inflammatory enzymes iNOS and COX-2. This compound exhibits anti-inflammatory properties by reducing pro-inflammatory cytokines, such as IL-1β, IL-6, and TNF-α, without significant cytotoxicity.
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O(C)C1=C2N(C[C@]3(N(C2=O)[C@H](C)CCO3)[H])C=C(C(NC4=CC(=CC=C4)C5=CN(N=N5)C6=C(Cl)C=CC=C6)=O)C1=O
Molecular Formula
C28H25ClN6O5
Molecular Weight
560.988
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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