STAT1/3-IN-1

• Target:

  COX|||STAT|||Interleukin|||NO Synthase

• Related Pathways:

  Neuroscience|||JAK/STAT signaling|||Stem Cells|||Immunology/Inflammation

• Bioactivity:

  STAT1/3-IN-1 (Compound 6k) is an inhibitor of STAT1/3 phosphorylation. It prevents the phosphorylation and nuclear translocation of STAT1/3. Additionally, STAT1/3-IN-1 inhibits the inflammatory enzymes iNOS and COX-2. This compound exhibits anti-inflammatory properties by reducing pro-inflammatory cytokines, such as IL-1?, IL-6, and TNF-?, without significant cytotoxicity.

• Smiles:

  O(C)C1=C2N(C[C@]3(N(C2=O)[C@H](C)CCO3)[H])C=C(C(NC4=CC(=CC=C4)C5=CN(N=N5)C6=C(Cl)C=CC=C6)=O)C1=O

• Molecular Formula:

  C28H25ClN6O5

• Molecular Weight:

  560.988

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2958649-56-2