Products for Research Use Only
RegisterLogin

PDHK1-IN-1

CAT: 0931-T205235-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T205235-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
PDHK1-IN-1 (compound 17) is a selective inhibitor of PDHK1 with an IC50 value of 1.5 μM, demonstrating anticancer properties. PDHK1 negatively regulates the pyruvate dehydrogenase complex (PDC), thereby restricting the tricarboxylic acid (TCA) cycle and oxidative phosphorylation. Overexpression of PDHK1 leads to increased reliance on glycolysis (Warburg effect) . PDHK1-IN-1 inhibits phosphorylation at the PDHK1 recognition site PDC E1α Ser232 and also suppresses phosphorylation of Ser293.
Molecular Formula
C14H11BrClNO4S
Molecular Weight
404.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T206446-01PDHK1-IN-2
T206155-01PDHK1-IN-3
T5790-011,1,1,1-Kestohexaose
T83125-01AMPK-α1β1γ1 activator 1
T404761,1,1-Tribromoacetone
T63327-01PDHK-IN-5
T62407-01PDHK-IN-4
T60527-01PDHK-IN-3
T88769-01PDHK-IN-7
T78868-01TWIK-1/TREK-1-IN-1

Alternative Products

CatalogName
HY-170838PDHK1-IN-1
HY-173298PDHK1-IN-2
GTR19258733-01PDHK1-IN-3
MBS517446-01PDHK1, Active
AF6586-01PDHK1 Antibody
AF6586-BPPDHK1 Peptide
MBS9617688-01PDHK1 Blocking Peptide
ES6557-01PDHK1 rabbit pAb
C05156-100uL*2PDHK1 Rabbit mAb
512625PDK1 (PDHK1) discontinued

Popular Products