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CST 530

CAT: 0931-T205007-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T205007-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
847137-53-5
Target
Ligand for E3 Ligase|||Apoptosis|||IAP
Related Pathways
PROTAC|||Apoptosis
Bioactivity
CST 530 is a monovalent IAP antagonist. It induces cIAP1 and cIAP2 autodegradation in MM.1S cells (cIAP1 degradation at 0.1 ?M and cIAP2 degradation at 1 ?M after 16 hours) . CST 530 reduces cell viability in multiple cancer cell lines including SUDHL6, MOLM13, and HEL (IC50 values ??of 170 nM, 420 nM, and 450 nM, respectively) .
Smiles
C([C@@H](NC([C@@H](NC)C)=O)C1CCCCC1)(=O)N2[C@H](C(N[C@H]3C=4C(CCC3)=CC=CC4)=O)C[C@H](OC5=CC=CC=C5)C2
Molecular Formula
C33H44N4O4
Molecular Weight
560.727
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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