UCB-5307

• Target :

  TNF

• Related Pathways :

  Apoptosis

• Purity :

  0.9989

• Bioactivity :

  UCB-5307 is a small molecule compound that inhibits TNFR1 signal transduction and downstream function in vitro. The KD of human TNF? is 9 nM. The TNF was directly bound by slow binding kinetics, KD= 6 nM. UCB-5307 can pass through prefabricated hTNF/hTNFR1 complexes.

• Smiles :

  Cc1ccc(C)c(Cn2c(nc3ccccc23)C(O)c2ccncc2)c1

• Molecular Formula :

  C22H21N3O

• Molecular Weight :

  343.42

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1515887-44-1