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PARP1-IN-35

CAT: 0013-GTR19249853-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249853-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PARP1-IN-35 (T26) is a brain-penetrant, orally bioavailable, and highly selective PARP1 inhibitor with an IC50 of 0.2 nM. It demonstrates potent antiproliferative effects in cellular assays and has shown promising in vivo efficacy in preclinical models of BRCA-mutant cancers, supporting its research utility in oncology, particularly for breast cancer.
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Smiles
CCC1=CC2=C (C=C (C=N2) CN3CCC (=CC3) C4=NC=C (C=C4) C#N) NC1=O
Molecular Formula
C22H21N5O
Molecular Weight
371.435
Storage Conditions
-20°C
Notes
For research use only.

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