BA-AZT1

• Target:

  HBV

• Related Pathways:

  Microbiology/Virology

• Bioactivity:

  BA-AZT1 acts as an inhibitor of HBV polymerase (HBV polymerase) and sodium taurocholate cotransporting polypeptide (NTCP) . It hinders the secretion of viral capsid proteins HBsAg and HBeAg, with IC50 values of 0.65 µM and 13.42 µM, respectively, and inhibits HBV DNA replication with an IC50 of 0.70 µM.

• Smiles:

  CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)N3C=C(N=N3)CO[C@H]4CC[C@@]5([C@H]6CC[C@@H]7[C@@H]8[C@@H](CC[C@@]8(CC[C@]7([C@@]6(CC[C@H]5C4(C)C)C)C)C(=O)O)C(=C)C)C

• Molecular Formula:

  C43H63N5O7

• Molecular Weight:

  761.99

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C