Products for Research Use Only

HDAC1-IN-8

CAT: 0931-T204224-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204224-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3066143-73-2
Target
Autophagy, HDAC
Related Pathways
Chromatin/Epigenetic, DNA Damage/DNA Repair, Autophagy
Bioactivity
HDAC1-IN-8 (compound 5c) is a potent and selective HDAC1 inhibitor, with IC50 values of 11.94 μM for HDAC1, 22.95 μM for HDAC6, and greater than 500 μM for HDAC8. It exhibits antiproliferative activity, induces cell cycle arrest in G1 and G2/M phases, and triggers autophagy (autophagy) . Additionally, HDAC1-IN-8 demonstrates anticancer properties and holds potential for lung cancer research.
Smiles
O=C(NO)CCCCCOC=1C=CC2=NC(=CC=C2C1)C3=CC=C(OC)C=C3
Molecular Formula
C22H24N2O4
Molecular Weight
380.437
Shipping Conditions
Ice Packs
Storage Temperature
-20°C