TRF2-IN-1

• Target:

  Telomerase|||Apoptosis

• Related Pathways:

  DNA Damage/DNA Repair|||Apoptosis

• Bioactivity:

  TRF2-IN-1 (compound F2) is a potent inhibitor of telomere repeat-binding factor 2 (TRF2) . It exhibits antiproliferative activity and induces apoptosis. TRF2-IN-1 binds directly to the TRF2TRFH domain, selectively inhibiting TRF2 protein expression and telomere localization. Additionally, TRF2-IN-1 possesses anticancer properties and shows potential for osteosarcoma research.

• Smiles:

  COC1=CC(=C(C(=C1)OC)C(=O)/C=C/C2=CC(=CC=C2)Br)OC

• Molecular Formula:

  C18H17BrO4

• Molecular Weight:

  377.229

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C