M351-0056

• Bioactivity:

  M351-0056 is an agonist of the immune checkpoint protein VISTA, diminishing cytokine secretion induced by VISTA, enhancing VISTA-induced T cell proliferation, and exhibiting immunomodulatory activity. Additionally, M351-0056 has been shown to improve psoriasis-like dermatitis induced by Imiquimod in mouse models.

• Smiles:

  O=S(=O)(NC1=CC=C(Br)C=C1F)C=2C=C(SC2C)C=3N=C(SC3)C

• Molecular Formula:

  C15H12BrFN2O2S3

• Molecular Weight:

  447.365

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1189495-81-5