ASM-IN-3

• Target :

  Phospholipase

• Related Pathways :

  Metabolism

• Bioactivity :

  ASM-IN-3 (Compound 21b) is a selective acid sphingomyelinase (ASM) inhibitor that can penetrate the blood-brain barrier, with an IC50 of 3.37 ?M against purified human ASM. By inhibiting ASM activity in the hippocampus and promoting neurogenesis, ASM-IN-3 alleviates depressive-like behavior in reserpine-induced depressive rats.

• Smiles :

  O=C(NO)C=1ON=C(OCC2=CC=C(C=C2)C=3C=CC(Cl)=CC3)C1

• Molecular Formula :

  C17H13ClN2O4

• Molecular Weight :

  344.75

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2342576-75-2