ASM-IN-3

CAT: 0931-MF-0063334-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0063334-01Size:10 mg
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
2342576-75-2
Target
Phospholipase
Related Pathways
Metabolism
Bioactivity
ASM-IN-3 (Compound 21b) is a selective acid sphingomyelinase (ASM) inhibitor that can penetrate the blood-brain barrier, with an IC50 of 3.37 ?M against purified human ASM. By inhibiting ASM activity in the hippocampus and promoting neurogenesis, ASM-IN-3 alleviates depressive-like behavior in reserpine-induced depressive rats.
Smiles
O=C(NO)C=1ON=C(OCC2=CC=C(C=C2)C=3C=CC(Cl)=CC3)C1
Molecular Formula
C17H13ClN2O4
Molecular Weight
344.75
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Popular Products