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PARP1-IN-33

CAT: 0931-T203672-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203672-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2640677-68-3
Target
PARP
Related Pathways
DNA Damage/DNA Repair, Chromatin/Epigenetic
Bioactivity
PARP1-IN-33 (Example 6) is a PARP1 inhibitor with an IC50 of 0.41 nM. It demonstrates protective effects on retinal cells, exhibiting an EC50 of 0.02 nM in inhibiting hydrogen peroxide-induced MTS activity in human retinal pigment epithelial cells.
Smiles
Cl.N#CC1=CC=C(C=C1)N2CCN(CC2)CCCC3=CC=4C=CC=C(F)C4C(=O)N3
Molecular Formula
C23H24ClFN4O
Molecular Weight
426.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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