Antibacterial agent 256

CAT: 0931-MF-0112556-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0112556-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3052804-28-8
Target
Others|||Antibacterial
Related Pathways
Others|||Microbiology/Virology
Bioactivity
Antibacterialagent 256 (Compound C09) is an inhibitor of Type I signal peptidase (SPase I) . It targets Gram-positive bacteria, effectively inhibiting S. aureus ATCC 29213, E. faecium QF31, E. faecalis SF23-1, and S. suis P1/7, with MIC values ranging from 1-16 ?g/mL. In cancer cells HEp-2 and Caco-2, Antibacterialagent 256 exhibits cytotoxicity with CC50 values of 14.65 ?g/mL and 21.93 ?g/mL, respectively. Additionally, it shows hemolytic activity on mouse red blood cells with an HC50 of 13.29 ?g/mL and can improve MRSA skin infections in mouse models.
Smiles
C(O)(=O)C1=C2C(\C(=C\C=3SC(=CC3)C4=CC(C(F)(F)F)=C(Cl)C=C4)\CC(C)C2)=NC=5C1=CC=CC5
Molecular Formula
C27H19ClF3NO2S
Molecular Weight
513.96
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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