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Lucidenic acid O

CAT: 0931-T203462-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203462-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
250643-33-5
Target
DNA/RNA Synthesis, HIV Protease, Reverse Transcriptase
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Proteases/Proteasome, Microbiology/Virology
Bioactivity
Lucidenic acid O is a terpene compound that acts as an inhibitor of DNA polymerases. Lucidenic lactone inhibits calf DNA polymerase-α, rat DNA polymerase-β, and HIV-1 reverse transcriptase, with IC50 values of 42 μM, 99 μM, and 69 μM, respectively.
Smiles
C[C@]12C3=C([C@]4(C)[C@@](C[C@@H]3O)([C@@](CO)(C)[C@@H](O)CC4)[H])C(=O)C[C@]1(C)[C@@H](C(CCC(O)=O)=C)C[C@@H]2O
Molecular Formula
C27H40O7
Molecular Weight
476.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C