Lucidenic lactone

• Target:

  HIV Protease|||Reverse Transcriptase|||DNA/RNA Synthesis

• Related Pathways:

  DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Microbiology/Virology|||Proteases/Proteasome

• Bioactivity:

  Lucidenic lactone is a terpene compound that acts as an inhibitor of DNA polymerases. It inhibits calf DNA polymerase-?, rat DNA polymerase-?, and HIV-1 reverse transcriptase with IC50 values of 42 ?M, 99 ?M, and 69 ?M, respectively.

• Smiles:

  C[C@@]12[C@](C)(C3=C(C(=O)C1)[C@]4(C)[C@@](C[C@@H]3O)(C(C)(C)[C@@H](O)CC4)[H])[C@@H](O)C[C@@H]2C5(CO)CCC(=O)O5

• Molecular Formula:

  C27H40O7

• Molecular Weight:

  476.6

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  250643-34-6