TB-9

CAT: 0931-T203408-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T203408-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1415033-91-8
Target
Cysteine Protease|||Beta-Secretase
Related Pathways
Neuroscience|||Proteases/Proteasome
Bioactivity
TB-9, a derivative of Tasiamide B, is a potent inhibitor of protease D (cathepsin D), protease E (cathepsin E), and BACE1, with IC50 values of 0.0783 nM, 0.724 nM, and 54.2 nM, respectively.
Smiles
C([C@@H](CC1=CC=CC=C1)N(C([C@@H](NC([C@@H](NC(C[C@@H]([C@H](CC2=CC=CC=C2)NC([C@@H](N(C([C@@H](NC(OCC3=CC=CC=C3)=O)C(C)C)=O)C)CCC(N)=O)=O)O)=O)CC(C)C)=O)C)=O)C)(=O)N4[C@H](C(OC)=O)CCC4
Molecular Formula
C55H76N8O12
Molecular Weight
1041.24
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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