TB-9

• Target :

  Cysteine Protease|||Beta-Secretase

• Related Pathways :

  Neuroscience|||Proteases/Proteasome

• Bioactivity :

  TB-9, a derivative of Tasiamide B, is a potent inhibitor of protease D (cathepsin D), protease E (cathepsin E), and BACE1, with IC50 values of 0.0783 nM, 0.724 nM, and 54.2 nM, respectively.

• Smiles :

  C([C@@H](CC1=CC=CC=C1)N(C([C@@H](NC([C@@H](NC(C[C@@H]([C@H](CC2=CC=CC=C2)NC([C@@H](N(C([C@@H](NC(OCC3=CC=CC=C3)=O)C(C)C)=O)C)CCC(N)=O)=O)O)=O)CC(C)C)=O)C)=O)C)(=O)N4[C@H](C(OC)=O)CCC4

• Molecular Formula :

  C55H76N8O12

• Molecular Weight :

  1041.24

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1415033-91-8