FRF-06-057

• Target:

  EGFR

• Related Pathways:

  Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling

• Bioactivity:

  FRF-06-057 is an allosteric ATP EGFR inhibitor targeting both wild-type and mutant EGFR, with IC50 values of 17 nM (LR/TM), 29 nM (LR/TM/CS), 220 nM (LR), and >1000 nM (WT) .

• Molecular Formula:

  C19H13N3O3S

• Molecular Weight:

  363.39

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C