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GAPDH-IN-1

CAT: 0931-T203346-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203346-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
252212-58-1
Target
Endogenous Metabolite
Related Pathways
Metabolism
Bioactivity
GAPDH-IN-1 (Compound F8) is a GAPDH inhibitor, with an IC50 value of 39.31 μM for GAPDH enzyme activity. It forms a covalent adduct with the aspartic acid in the active site, displacing the enzyme's cofactor NAD+, and simultaneously enhances the reactivity of cysteine-reactive probes with the catalytic cysteine.
Smiles
N=1N=C(OC1C=2C=CC=C(OCC3OC3)C2)C=4C=CC=C(OCC5OC5)C4
Molecular Formula
C20H18N2O5
Molecular Weight
366.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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