GAPDH-IN-1

• CAS Number :

  252212-58-1

• Target :

  Endogenous Metabolite

• Related Pathways :

  Metabolism

• Bioactivity :

  GAPDH-IN-1 (Compound F8) is a GAPDH inhibitor, with an IC50 value of 39.31 ?M for GAPDH enzyme activity. It forms a covalent adduct with the aspartic acid in the active site, displacing the enzyme's cofactor NAD+, and simultaneously enhances the reactivity of cysteine-reactive probes with the catalytic cysteine.

• Smiles :

  N=1N=C(OC1C=2C=CC=C(OCC3OC3)C2)C=4C=CC=C(OCC5OC5)C4

• Molecular Formula :

  C20H18N2O5

• Molecular Weight :

  366.37

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C