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GAPDH

CAT: 0209-102-P93SSize: 100 μgDry Ice: NoHazardous: No
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CAT#:0209-102-P93SSize:100 μg
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Description
GAPDH (Glyceraldehyde-3-phosphate dehydrogenase) is a catalytic enzyme commonly known to be involved in glycolysis. GAPDH catalyzes the conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate and the reverse reaction during gluconeogenesis. Due to its nitrosylase activity, GAPDH is also involved in nuclear processes including transcription, binding RNA, RNA transportation, DNA replication, DNA repair and apoptosis. Being stably and constitutively expressed at high levels in most tissues and cells, GAPDH is considered a housekeeping protein and is therefore widely used as a control for RT-PCR, electrophoresis or Western blot analyses.
Synonyms
Glyceraldehyde-3-phosphate dehydrogenase, Peptidyl-cysteine S-nitrosylase GAPDH, GAPD, CDABP0047, G3PD, HEL-S-162eP
NCBI Gene ID
2597
UniProt
P04406
Accession Number
NP_002037.2
Accession Number mRNA
NM_002046.7
Reactivity
Human
Target Antigen
Recombinant full-length human GAPDH
Applications
WB, ELISA, IHC
Purification Method
Antigen purified
Buffer
PBS
Additives
0.07% sodium azide
Storage Conditions
The antibody solution should be stored undiluted at -20°C.
Formulation
Liquid (1 mg/mL)
Host or Source
Human
Species
Anti-Human
Isotype
Rabbit IgG

UniProtKB · P04406

Glyceraldehyde-3-phosphate dehydrogenase

G3P_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P04406
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GAPDH
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
GAPDH
EC number
1.2.1.12
Processing
—
Secondary accessions
E7EUT4, P00354, Q53X65
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationADP-ribosylationGlycoproteinIsopeptide bondMethylationOxidationPhosphoproteinS-nitrosylationUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisGlycolysisImmunityInnate immunityTranslation regulation

Cellular component

CytoplasmCytoskeletonMembraneNucleus

Ligand

NAD

Molecular function

OxidoreductaseTransferase

Alternative Products

CatalogName
GTR18101746GAPDH, GAPDH Antibody
CSB-CL009232HUGAPDH

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