Products for Research Use Only

GAPDH-IN-1

CAT: 0013-GTR19241296-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19241296-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GAPDH-IN-1 (Compound F8) is a covalent GAPDH inhibitor with an IC50 of 39.31 μM. It acts by displacing NAD+ from the active site and covalently modifying an aspartic acid residue, which concurrently sensitizes the catalytic cysteine to thiol-reactive probes. This inhibitor is a useful chemical tool for studying glycolytic inhibition and redox signaling in cellular models.
CAS Number
252212-58-1
Field of Research
Metabolism Research
Smiles
N=1N=C (OC1C=2C=CC=C (OCC3OC3) C2) C=4C=CC=C (OCC5OC5) C4
Molecular Formula
C20H18N2O5
Molecular Weight
366.37
Storage Conditions
-20°C
Notes
For research use only.