Products for Research Use Only

KIF18A-IN-15

CAT: 0931-T203212-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203212-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3051552-64-5
Target
Kinesin
Related Pathways
Cytoskeletal Signaling
Bioactivity
KIF18A-IN-15 (Compound Example 36) is a KIF18A inhibitor, available in two forms, EX36-A and its enantiomer EX36-B, both with an IC50 range of 0.01-0.1 μM. These compounds inhibit the viability of OVCAR-3 cells, with IC50 values of 0.01-0.1 μM for EX36-A and 0-0.01 μM for EX36-B. KIF18A-IN-15 is applicable in research on tumors, including colon, breast, and lung cancers.
Smiles
O=C1NC2=CC(=NC(=NCC(C)COCC3(CCN(C4=CC(=CC=C14)NS(=O)(=O)CCO)CC3)C(F)(F)F)N2)C
Molecular Formula
C25H33F3N6O5S
Molecular Weight
586.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C