Products for Research Use Only

KIF18A-IN-14

CAT: 0931-T203056-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203056-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3051552-75-8
Target
Kinesin
Related Pathways
Cytoskeletal Signaling
Bioactivity
KIF18A-IN-14 (Compound Example 81) is an inhibitor of KIF18A that exists in two forms, EX81-A and its enantiomer EX81-B. EX81-A and EX81-B inhibit the viability of OVCAR-3 cells with IC50 values of 0-0.01 μM and 0.01-0.1 μM, respectively. KIF18A-IN-14 can be utilized in tumor research, including studies on colon cancer, breast cancer, and lung cancer.
Smiles
O=C1NC=2N=C(C=CC2)N3CCOC(COCC4(CCN(C5=CC(=CC=C15)NS(=O)(=O)CCO)CC4)C(F)(F)F)C3
Molecular Formula
C26H32F3N5O6S
Molecular Weight
599.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C