PSB-22269

CAT: 0931-T203177-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T203177-01Size:10 mg
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Orphan Receptor|||Others
Related Pathways
GPCR/G Protein|||Others
Bioactivity
PSB-22269 is identified as a GPR17 antagonist with a Ki value of 8.91 nM. It exhibits significant inhibitory effects in cAMP and G protein activation assays. Molecular docking studies indicate that the binding site of PSB-22269 includes positively charged arginine residues and a hydrophobic pocket. PSB-22269 promotes myelin regeneration strategies, offering potential for multiple sclerosis research.
Molecular Formula
C26H21NO6
Molecular Weight
443.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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