PSB-22269

• Target:

  Orphan Receptor|||Others

• Related Pathways:

  GPCR/G Protein|||Others

• Bioactivity:

  PSB-22269 is identified as a GPR17 antagonist with a Ki value of 8.91 nM. It exhibits significant inhibitory effects in cAMP and G protein activation assays. Molecular docking studies indicate that the binding site of PSB-22269 includes positively charged arginine residues and a hydrophobic pocket. PSB-22269 promotes myelin regeneration strategies, offering potential for multiple sclerosis research.

• Molecular Formula:

  C26H21NO6

• Molecular Weight:

  443.45

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C