LDHA-IN-9

• Target:

  Apoptosis|||Dehydrogenase

• Related Pathways:

  Metabolism|||Apoptosis

• Bioactivity:

  LDHA-IN-9 (Compound 1g) is an LDH-A inhibitor with an IC50 of 25 nM. It inhibits the proliferation of DLD-1 cells by inducing apoptosis, with a GI50 of 27 ?M. In mouse models, LDHA-IN-9 exhibits antitumor activity without significant toxicity at a dose of 25 mg/kg.

• Smiles:

  O=C (OC) C1=C (C=2C (Br) =CC=CC2N1O) COCCCCCC

• Molecular Formula:

  C17H22BrNO4

• Molecular Weight:

  384.27

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  862719-04-8