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APOL1-IN-2

CAT: 0931-T203030-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203030-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2956781-84-1
Target
Apolipoprotein
Related Pathways
Metabolism
Bioactivity
APOL1-IN-2 (Compound 467) acts as an inhibitor of apolipoprotein L1 (APOL1) . It effectively reduces HEK293 cell death induced by APOL1 G2/G1, with EC50 values of 4.74 nM and 14.3 nM, respectively. Additionally, APOL1-IN-2 decreases the mortality of trypanosomes triggered by APOL1 G2/G1/G0, with EC50 values of 2.24, 6.03, and 3.72 nM, respectively.
Smiles
O=C1C2(C=3C(N1)=CC=C(Cl)C3)CCN(CCOC=4C=C5C(=C(C(F)(F)F)C4)N(C(=O)N5CO)[C@H]6C[C@@](C)(O)C6)CC2
Molecular Formula
C28H30ClF3N4O5
Molecular Weight
595.01
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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