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APOL1-IN-2

CAT: 0804-HY-169932Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-169932Size:1 Each
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Description
APOL1-IN-2 (Compound 467) is the inhibitor for Apolipoprotein 1 (APOL1) . APOL1-IN-2 reduces the APOL1 G2/G1 induced cell death in HEK293 with EC50 of 4.74 nM and 14.3 nM. APOL1-IN-2 reduces the APOL1 G2/G1/G0 induced death of trypanosomes with EC50 of 2.24, 6.03 and 3.72 nM, respectively[1].
CAS Number
2956781-84-1
UNSPSC
12352005
Target
Apolipoprotein
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
O=C(N1[C@@H]2C[C@](C)(O)C2)N(CO)C3=C1C(C(F)(F)F)=CC(OCCN(CC4)CCC4(C(N5)=O)C6=C5C=CC(Cl)=C6)=C3
Molecular Formula
C28H30ClF3N4O5
Molecular Weight
595.01
References & Citations
[1]Lee PST, et al., APOL1 inhibitors and methods of use. US11976067B2
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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