Products for Research Use Only

EGFR-IN-156

CAT: 0013-GTR19258312-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258312-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR-IN-156 (Compound 7f) is an EGFR inhibitor with inhibitory activity against mutant EGFRL858R and EGFRT790M, with IC50 values of 0.186, 0.131, and 0.107 μM, respectively. It exhibits significant anticancer activity against human cancer cell lines HepG-29 (liver cancer), MCF-7 (breast cancer), and HCT-116 (colon cancer), with IC50 values of 1.67, 5.32, and 6.56 μM, respectively. EGFR-IN-156 suppresses cancer cell proliferation by inducing cell cycle arrest at the G/G1 phase and triggering apoptosis. It shows potential in EGFR-related cancers.
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Molecular Formula
C27H26N4O7S
Storage Conditions
-20°C
Notes
For research use only.