GPD-1116

• Target:

  Ligand for E3 Ligase|||Apoptosis

• Related Pathways:

  PROTAC|||Apoptosis

• Bioactivity:

  GPD-1116 is an orally active inhibitor of phosphodiesterase (PDE) 4 and PDE1. The compound effectively reduces smoke-induced apoptosis in lung cells. Additionally, GPD-1116 has shown efficacy in various animal disease models, including emphysema, acute lung injury, chronic obstructive pulmonary disease (COPD), asthma, and pulmonary arterial hypertension.

• Smiles:

  O=C1C=2C(=NNC2C=3C=CC=NC3N1C=4C=CC=CC4)CC=5C=CC=CC5

• Molecular Formula:

  C22H16N4O

• Molecular Weight:

  352.39

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  690690-72-3