SDU-071

• Target:

  Apoptosis|||Epigenetic Reader Domain

• Related Pathways:

  Apoptosis|||Chromatin/Epigenetic

• Purity:

  0.9954

• Bioactivity:

  SDU-071 is an orally active BRD4-p53 inhibitor, inhibiting the proliferation of MDA-MB-231 cells, blocking the interaction between BRD4 and the tumor suppressor p53, downregulating the expression of BRD4-targeted genes, thereby inhibiting cell proliferation, migration, and invasion, and inducing cell cycle arrest and apoptosis. SDU-071 is used for research on triple-negative breast cancer.

• Smiles:

  COC(C=C1)=CC=C1NCC(C=C2NC3=CC=C(OC)C=C3)=NC4=C2C=CC5=C4C=CC=C5

• Molecular Formula:

  C28H25N3O2

• Molecular Weight:

  435.52

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3036109-10-8