JWG-071

• Target:

  Epigenetic Reader Domain|||ERK

• Related Pathways:

  MAPK|||Chromatin/Epigenetic

• Purity:

  0.9983

• Bioactivity:

  JWG-071, the first reported chemical probe for ERK5 kinase selectivity, is a BET-selective inhibitor with a 1 ?M BRD4 IC that enhances both ERK5 activity and BRD4 selectivity.

• Smiles:

  CCC(C)N1c2ccccc2C(=O)N(C)c2cnc(Nc3ccc(cc3OC)C(=O)N3CCC(CC3)N3CCN(C)CC3)nc12

• Molecular Formula:

  C34H44N8O3

• Molecular Weight:

  612.77

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2250323-50-1