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HSP90-IN-33

CAT: 0931-T201275-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T201275-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis, HSP
Related Pathways
Apoptosis, Cytoskeletal Signaling, Metabolism
Bioactivity
HSP90-IN-33 (compound 24e) is an effective Hsp90 inhibitor, demonstrating dissociation constants (Kd) of ≥200 μM for Hsp90α and 7.3 μM for Hsp90β. This compound induces cellular apoptosis (apoptosis) and arrests the cell cycle at the G0/G1 phase. Additionally, HSP90-IN-33 reduces the protein expression of ERα, CDK4, and Akt.
Molecular Formula
C21H25Cl2N5O2
Molecular Weight
450.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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