XH161-180

• Target:

  DUB

• Related Pathways:

  Ubiquitination|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint

• Bioactivity:

  XH161-180 is an effective and orally active inhibitor of ubiquitin carboxyl-terminal hydrolase 2 (USP2) . It reduces the protein levels of cyclin D and ACE2, exhibiting antiproliferative activity. XH161-180 also has potential for research in cancers and viral infections that depend on ACE2.

• Smiles:

  O=C(NC1=NC(=CS1)C=2C=CC(Br)=CC2)C3=CC=C(F)C=C3NS(=O)(=O)C4CCCCC4

• Molecular Formula:

  C22H21BrFN3O3S2

• Molecular Weight:

  538.45

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3058588-52-3