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NLRP3-IN-58

CAT: 0931-T200969-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T200969-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2956014-05-2
Target
NOD-like Receptor (NLR), Interleukin
Related Pathways
Immunology/Inflammation
Bioactivity
NLRP3-IN-58 (Compound DS15) acts as an inhibitor of NLRP3 inflammasome activation, with an IC50 value of 3.85 μM, and is capable of inhibiting 33% of IL-1β release at a concentration of 10 μM.
Smiles
O=C(NC1=CC=CC(=C1)S(=O)(=O)NC=2C=CC=CC2)CC3=CNC=4C=C(Cl)C=CC43
Molecular Formula
C22H18ClN3O3S
Molecular Weight
439.92
Shipping Conditions
Ice Packs
Storage Temperature
-20°C