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Toladryl

CAT: 0931-T200797-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T200797-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
19804-27-4
Target
Endogenous Metabolite, Histamine Receptor, iGluR
Related Pathways
Membrane transporter/Ion channel, GPCR/G Protein, Immunology/Inflammation, Neuroscience, Metabolism
Bioactivity
Toladryl is a derivative of Diphenhydramine that can cross the blood-brain barrier and exhibits oral activity, with antihistamine and anticholinergic properties. Its anticholinergic effects are approximately a tenth of those seen with Diphenhydramine, yet it offers 2-4 times the protection against lethal doses of histamine in guinea pigs. The side effects of Toladryl are fewer and milder compared to Diphenhydramine; however, at higher doses, it may cause symptoms such as insomnia, agitation, and disorientation related to the central nervous system. Toladryl is utilized in the research of allergic diseases.
Smiles
O(CCN(C)C)C(C=1C=CC=CC1)C2=CC=C(C=C2)C
Molecular Formula
C18H23NO
Molecular Weight
269.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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