INOs-IN-5

CAT: 0931-MF-0110409-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0110409-01Size:10 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis|||NO Synthase
Related Pathways
Apoptosis|||Immunology/Inflammation
Bioactivity
INOs-IN-5 (Compound BN-4) is an inhibitor of iNOS with an IC50 value of 0.1707 ?M, effectively reducing NO expression in RAW264.7 cells stimulated by LPS (HT-D1056) . It further diminishes the expression of ROS and lactate dehydrogenase induced by hypoxic injury, displaying anti-necrotic and anti-apoptotic properties. In an SD rat model, iNOs-IN-5 exhibits neuroprotective effects against cerebral ischemia and is capable of crossing the blood-brain barrier.
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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