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SARS-CoV-IN-6

CAT: 0931-T200730-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T200730-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2244671-47-2
Target
SARS-CoV
Related Pathways
Microbiology/Virology
Bioactivity
SARS-CoV-IN-6 (Compound 17) acts as an inhibitor of SARS-CoV-1 and SARS-CoV-2 RdRp, demonstrating an IC50 value of 7.8 μM against SARS-CoV-2 RdRp. This compound reduces the cytopathic effects of single-round infectious particles (SRIP) infected with SARS-CoV-1 and SARS-CoV-2 replicons and inhibits the expression of SARS-CoVN proteins. The EC50 values for SRIP based on SARS-CoV-1 and SARS-CoV-2 replicons are 0.12 μM and 1.47 μM, respectively.
Smiles
C(N1C[C@@]2(C=3N(C[C@@](C2)(C1)[H])C(=O)C(NCC=4C(=O)N(C)C(=O)N(C)C4)=CC3)[H])C5=CC=CC=C5
Molecular Formula
C25H29N5O3
Molecular Weight
447.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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