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CV-4-26

CAT: 0931-T200708-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T200708-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis, YAP
Related Pathways
Stem Cells, Apoptosis
Bioactivity
CV-4-26 (Compound 22) acts as a covalent inhibitor of TEAD. By inhibiting YAP/TEAD-driven transcription, it diminishes the expression of CTGF and CYR61. Furthermore, CV-4-26 impedes colony formation in Huh7 and HepG2 cells, inducing cell cycle arrest and apoptosis (apoptosis) . This compound demonstrates anti-tumoral activity against hepatocellular carcinoma (HCC) and hepatoblastoma (HB) .
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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