Products for Research Use Only

NOD1-IN-1

CAT: 0931-T200671-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T200671-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
687627-78-7
Target
NOD-like Receptor (NLR)
Related Pathways
Immunology/Inflammation
Bioactivity
NOD1/2-IN-1 (Compound 2) is a potent inhibitor of RIPK2 with an IC50 value of 0.65 nM as determined by the ADP-Glo assay. It selectively inhibits the NOD1 pathway, with an IC50 of 33 nM, effectively blocking the production of pro-inflammatory cytokines and thereby reducing inflammatory responses. This compound has potential applications in the research of colitis.
Smiles
ClC1=CC=C(C=C1O)NC=2N=CN=C3C=C(OC)C(OC)=CC32
Molecular Formula
C16H14ClN3O3
Molecular Weight
331.75
Shipping Conditions
Ice Packs
Storage Temperature
-20°C