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NOD2 antagonist 1

CAT: 0931-T63088-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T63088-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2411441-54-6
Target
NOD-like Receptor (NLR), Others
Related Pathways
Immunology/Inflammation, Others
Bioactivity
NOD2 antagonist 1 (compound 32) is an effective and selective NOD2 antagonist (IC50: 5.23 μM) . In THP-1 cells, it represses Muramyl DiDP (MDP) -induced IL-8 secretion and, in PBMCs cells, inhibits MDP-induced elevation of IL-6, IL-10, and TNF-α.
Smiles
C(C(NC=1C=C2C(=CC1)CCC2)=O)N3C=4C(N=C3CCNS(=O)(=O)C5=CC=CC=C5)=CC=CC4
Molecular Formula
C26H26N4O3S
Molecular Weight
474.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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