NOD1 antagonist-1

• UNSPSC Description:

  NOD1 antagonist-1 (compound 37) exhibits an antagonistic activity towards NOD1 and a weak NOD1/NOD2 selectivity, with IC50s of 9.18 μM and 20.8 μM, respectively[1].

• Target Antigen:

  NOD-like Receptor (NLR)

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/nod1-antagonist-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=CC=C(S(N2C3=CC=CC=C3C(N4CCN(CC4)C)=C2NC(C)(C)C)(=O)=O)C=C1

• Molecular Weight:

  440.60

• References & Citations:

  [1]Russo C,et al., Discovery of 2,3-Diaminoindole Derivatives as a Novel Class of NOD Antagonists. J Med Chem. 2024 Feb 1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported