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Bayer-18

CAT: 0931-T200632-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T200632-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1251752-12-1
Target
Apoptosis, JAK
Related Pathways
Stem Cells, Chromatin/Epigenetic, Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Apoptosis
Bioactivity
Bayer-18 is an inhibitor of TYK2. It inhibits the viability of anaplastic large cell lymphoma cells, including K299, SR786, Mac1, and Mac2a, with an IC50 ranging from 2-3 μM. Additionally, Bayer-18 induces apoptosis in K299 and SR786 cells.
Smiles
O=C(NC1=CC=CC(=C1)NC2=NC=C(F)C(=N2)NC(C)(C)CO)NC(C)(C)C
Molecular Formula
C19H27FN6O2
Molecular Weight
390.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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