Bayer-18

• CAS Number :

  1251752-12-1

• Target :

  Apoptosis|||JAK

• Related Pathways :

  Stem Cells|||Chromatin/Epigenetic|||Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Apoptosis

• Bioactivity :

  Bayer-18 is an inhibitor of TYK2. It inhibits the viability of anaplastic large cell lymphoma cells, including K299, SR786, Mac1, and Mac2a, with an IC50 ranging from 2-3 µM. Additionally, Bayer-18 induces apoptosis in K299 and SR786 cells.

• Smiles :

  O=C(NC1=CC=CC(=C1)NC2=NC=C(F)C(=N2)NC(C)(C)CO)NC(C)(C)C

• Molecular Formula :

  C19H27FN6O2

• Molecular Weight :

  390.46

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C