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CDK9-IN-34

CAT: 0931-T200619-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T200619-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
252725-86-3
Target
SARS-CoV, CDK
Related Pathways
Microbiology/Virology, Cell Cycle/Checkpoint
Bioactivity
CDK9-IN-34 (Compound 1b) is an inhibitor of CDK9 with an IC50 of 0.25 μM. It exhibits cytotoxicity against cancer cell lines HCT116, MCF7, and K652, with IC50 values of 1.43 μM, 3.01 μM, and 50.27 μM, respectively. Additionally, CDK9-IN-34 demonstrates antiviral activity against coronavirus 229E with an IC50 of 145.92 μM.
Smiles
N=1C=CN2C(=NC(C=3C=CC=CC3)=C2NC4CCCCC4)C1
Molecular Formula
C18H20N4
Molecular Weight
292.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C