CDK9-IN-34

• Target:

  SARS-CoV|||CDK

• Related Pathways:

  Microbiology/Virology|||Cell Cycle/Checkpoint

• Bioactivity:

  CDK9-IN-34 (Compound 1b) is an inhibitor of CDK9 with an IC50 of 0.25 ?M. It exhibits cytotoxicity against cancer cell lines HCT116, MCF7, and K652, with IC50 values of 1.43 ?M, 3.01 ?M, and 50.27 ?M, respectively. Additionally, CDK9-IN-34 demonstrates antiviral activity against coronavirus 229E with an IC50 of 145.92 ?M.

• Smiles:

  N=1C=CN2C (=NC (C=3C=CC=CC3) =C2NC4CCCCC4) C1

• Molecular Formula:

  C18H20N4

• Molecular Weight:

  292.38

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  252725-86-3